The National Weather Service is warning of “major travel disruptions” in the Louisville area Wednesday afternoon and Thursday morning because of a major snowstorm heading into the region.

Louisville may get as much as a foot of snow from the storm, the National Weather Service said in a Tuesday afternoon update.

Before the snow, authorities are warning of possible flooding from heavy rains through Wednesday morning.

The rain is expected to transition to snow in Louisville by mid-afternoon Wednesday (and earlier in Southern Indiana, which may get as much as nine inches of snow), according to the National Weather Service. So the Wednesday afternoon commute may be tricky for people in the Louisville area.

There’s more—the National Weather Service forecasts that low temperatures Friday morning may reach close to zero in Louisville.